Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779995 | 0.82 | MEN1 (0.39) | TSHRMEN1KMT2AGAAMMP2 | |
| SCHEMBL9779976 | 0.80 | ALOX5 (0.51) | DRD2MEN1KMT2AGAAALOX5 | |
| SCHEMBL9780043 | 0.79 | ALDH1A1 (0.42) | TSHRMEN1KMT2AGAAPOLB | |
| SCHEMBL9780037 | 0.79 | ALOX5 (0.46) | GAAALOX5POLB | |
| SCHEMBL9779956 | 0.78 | ALOX5 (0.53) | HTR1AMEN1KMT2AGAAALOX5 | |
| SCHEMBL9779963 | 0.77 | ALOX5 (0.50) | MMP2ALOX5POLB | |
| SCHEMBL9780008 | 0.75 | ALOX5 (0.55) | MEN1KMT2AGAAALOX5 | |
| SCHEMBL9779986 | 0.75 | G6PD (0.47) | PTGS2GAAALOX5 | |
| SCHEMBL9779987 | 0.74 | MEN1 (0.37) | TSHRDRD2MEN1KMT2AGAA | |
| SCHEMBL9779977 | 0.74 | FAAH (0.42) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |