Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779963 | 0.84 | ALOX5 (0.50) | POLBGSK3AGSK3BMGLLMMP2 | |
| SCHEMBL9780037 | 0.83 | ALOX5 (0.46) | POLBGAAALOX5ALDH1A1MAPT | |
| SCHEMBL9779986 | 0.82 | G6PD (0.47) | GAAGSK3AGSK3BALOX5 | |
| SCHEMBL9779997 | 0.82 | BPTF (0.38) | MEN1POLBGAAKMT2AMMP2 | |
| SCHEMBL9779976 | 0.81 | ALOX5 (0.51) | MEN1POLBGAAKMT2AMGLL | |
| SCHEMBL9780007 | 0.80 | POLB (0.49) | MEN1POLBGAAKMT2AGSK3A | |
| SCHEMBL9779945 | 0.78 | L3MBTL1 (0.36) | ALOX5 | |
| SCHEMBL9780043 | 0.77 | ALDH1A1 (0.42) | MEN1POLBGAAKMT2ANPC1 | |
| SCHEMBL9779987 | 0.75 | MEN1 (0.37) | MEN1POLBGAAKMT2AALDH1A1 | |
| SCHEMBL9780031 | 0.73 | MEN1 (0.51) | MEN1KMT2AMGLLALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | claimed |
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |