Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779963 | 0.84 | ALOX5 (0.50) | ALOX5GSK3AGSK3B | |
| SCHEMBL9779995 | 0.82 | MEN1 (0.39) | GAAALOX5GSK3AGSK3B | |
| SCHEMBL9779956 | 0.82 | ALOX5 (0.53) | GAAALOX5 | |
| SCHEMBL9780008 | 0.82 | ALOX5 (0.55) | GAAL3MBTL1ALOX5 | |
| SCHEMBL9779977 | 0.80 | FAAH (0.42) | ALOX5 | |
| SCHEMBL10413890 | 0.80 | ADRA2C (0.45) | ALOX5ALOX15 | |
| SCHEMBL9779936 | 0.80 | MEN1 (0.44) | L3MBTL1ALOX5 | |
| SCHEMBL9780040 | 0.80 | ALOX5 (0.52) | GAAL3MBTL1ALOX5GSK3AGSK3B | |
| SCHEMBL9779976 | 0.80 | ALOX5 (0.51) | GAAL3MBTL1ALOX5 | |
| SCHEMBL9779943 | 0.80 | NPC1 (0.49) | L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | claimed |
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |