Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780037 | 0.84 | ALOX5 (0.46) | ALOX5ALDH1A1POLBGAAMAPT | |
| SCHEMBL9779956 | 0.83 | ALOX5 (0.53) | ALOX5ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL9780008 | 0.83 | ALOX5 (0.55) | ALOX5GAAMAPTMEN1KMT2A | |
| SCHEMBL10413890 | 0.82 | ADRA2C (0.45) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9780040 | 0.82 | ALOX5 (0.52) | ALOX5ALDH1A1POLBGAAMEN1 | |
| SCHEMBL9779977 | 0.82 | FAAH (0.42) | ALOX5FAAHMGLL | |
| SCHEMBL9779936 | 0.82 | MEN1 (0.44) | ALOX5ALDH1A1POLBMAPTMEN1 | |
| SCHEMBL9780010 | 0.81 | ALOX5 (0.54) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9779995 | 0.81 | MEN1 (0.39) | ALOX5ALDH1A1POLBGAAMAPT | |
| SCHEMBL9779980 | 0.81 | ALOX5 (0.55) | ALOX5MAPTMEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | claimed |