Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780007 | 0.83 | POLB (0.49) | MAPTMGLLADRB1MEN1KMT2A | |
| SCHEMBL9779956 | 0.82 | ALOX5 (0.53) | ALOX5MAPTMGLLADRB1CYP1A2 | |
| SCHEMBL9780008 | 0.82 | ALOX5 (0.55) | ALOX5MAPTMGLLADRB1MEN1 | |
| SCHEMBL10413890 | 0.81 | ADRA2C (0.45) | ALOX5MAPTMEN1KMT2A | |
| SCHEMBL9780040 | 0.81 | ALOX5 (0.52) | ALOX5MGLLMEN1KMT2AALKBH5 | |
| SCHEMBL9779936 | 0.81 | MEN1 (0.44) | ALOX5MAPTMEN1KMT2ADRD2 | |
| SCHEMBL9779976 | 0.81 | ALOX5 (0.51) | ALOX5MAPTMGLLMEN1KMT2A | |
| SCHEMBL9779977 | 0.81 | FAAH (0.42) | ALOX5MGLL | |
| SCHEMBL9779946 | 0.80 | ALOX5 (0.59) | ALOX5MEN1KMT2A | |
| SCHEMBL9779986 | 0.79 | G6PD (0.47) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |