Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9780008 | 0.83 | ALOX5 (0.55) | MGLLALOX5 | |
| SCHEMBL9779956 | 0.83 | ALOX5 (0.53) | MGLLALOX5 | |
| SCHEMBL10413890 | 0.82 | ADRA2C (0.45) | ALOX5 | |
| SCHEMBL9779936 | 0.82 | MEN1 (0.44) | ALOX5 | |
| SCHEMBL9779976 | 0.82 | ALOX5 (0.51) | FAAHMGLLALOX5 | |
| SCHEMBL9780040 | 0.82 | ALOX5 (0.52) | MGLLALOX5 | |
| SCHEMBL9779980 | 0.81 | ALOX5 (0.55) | MGLLALOX5 | |
| SCHEMBL9779986 | 0.80 | G6PD (0.47) | ALOX5 | |
| SCHEMBL9780010 | 0.78 | ALOX5 (0.54) | ALOX5 | |
| SCHEMBL9780062 | 0.78 | ALOX5 (0.54) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |