Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | MMP14 | P50281 | 5/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341921 | 0.87 | CA2 (0.51) | PSIP1CA2CA1CA9CA12 | |
| SCHEMBL15711923 | 0.83 | CA2 (0.47) | PSIP1CA2MAPTKDM4ELOX | |
| SCHEMBL314732 | 0.82 | TSHR (0.50) | CA2CA1CA9CA12CA4 | |
| SCHEMBL10787889 | 0.82 | MMP2 (0.47) | CA2MAPTKDM4ESMN1; SMN2MMP2 | |
| SCHEMBL10700258 | 0.82 | LMNA (0.45) | CA2SMN1; SMN2MMP2MMP8MMP14 | |
| SCHEMBL10951462 | 0.80 | MMP1 (0.43) | CA2CA1CA9CA12CA7 | |
| SCHEMBL2685459 | 0.79 | ALDH1A1 (0.60) | MAPT | |
| SCHEMBL8818862 | 0.79 | CA2 (0.39) | CA2MAPTMMP2MMP8MMP14 | |
| SCHEMBL19851244 | 0.79 | CA2 (0.41) | CA2CA1CA9CA12MMP2 | |
| SCHEMBL1171141 | 0.78 | HSD11B1 (0.50) | PSIP1MAPTSMN1; SMN2MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047515-A | Monoazo Dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4237050-A | Process for the preparation of water-soluble phthalocyanine dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |