Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783495 | 0.73 | CYP19A1 (0.37) | CYP19A1NPSR1 | |
| SCHEMBL9783361 | 0.71 | ALOX15B (0.36) | CYP19A1CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL9783376 | 0.70 | CYP2D6 (0.44) | CYP19A1MEN1GAAKMT2ACYP1A2 | |
| SCHEMBL9783945 | 0.68 | CYP19A1 (0.43) | CYP19A1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9783405 | 0.68 | P2RX7 (0.33) | GRM5ALDH1A1ALOX15NPSR1HSD17B10 | |
| SCHEMBL9783699 | 0.67 | KCNA5 (0.36) | GPBAR1KCNN4KCNA5GAACYP1A2 | |
| SCHEMBL9783414 | 0.66 | TLR8 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL9783833 | 0.66 | HSD11B1 (0.33) | CYP19A1GPBAR1GRM4GRM5MEN1 | |
| SCHEMBL9783879 | 0.65 | CYP19A1 (0.35) | CYP19A1ADRA1AMEN1KMT2ACYP17A1 | |
| SCHEMBL27819827 | 0.65 | KCNN4 (0.50) | ADRA1AGRM5KCNN4KCNA5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |