Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449766 | 0.94 | BACE1 (0.44) | GABRA1GABRB2BACE1ALDH1A1TDP1 | |
| SCHEMBL18925849 | 0.93 | HSP90AA1 (0.41) | GABRA1GABRB2BACE1ALDH1A1TDP1 | |
| SCHEMBL3818720 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KIF11ABL1 | |
| SCHEMBL20130330 | 0.85 | ALDH1A1 (0.52) | GABRA1GABRB2BACE1ALDH1A1TDP1 | |
| SCHEMBL15934242 | 0.84 | GABRA1 (0.34) | GABRA1GABRB2ALDH1A1TDP1CA1 | |
| SCHEMBL14805919 | 0.83 | TTR (0.41) | GABRA1GABRB2CA2MEN1KMT2A | |
| SCHEMBL15934277 | 0.80 | LMNA (0.32) | GABRA1GABRB2ALDH1A1CYP3A4TP53 | |
| SCHEMBL18925848 | 0.80 | KIF11 (0.35) | ALDH1A1KIF11MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14075676 | 0.78 | ALDH1A1 (0.61) | ALDH1A1CA1CA2CYP3A4TTR | |
| SCHEMBL15341308 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1CA2KIF11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504380-A | Liquid stabilizer for nitrate compound and preparation method thereof | 南京理工大学 | 2025-02-25 | — | — | CN | disclosed |
| US-10272079-B2 | NHE3-binding compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| US-20160067242-A1 | NHE3-BINDING COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2016-03-10 | — | — | US | disclosed |
| US-5072034-A | PREPARATION OF 4-ALKOXY-2-HYDROXYBENZOPHENONE-5-SULFONIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160067242-A1 | NHE3-BINDING COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | GABRA1 3559/4885GABRB2 2465/4885BACE1 4681/4885 |
| US-10272079-B2 | NHE3-binding compounds and methods for inhibiting phosphate transport | SLC34A3, SLC34A2, SLC34A1 | GABRA1 3559/4885GABRB2 2465/4885BACE1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.