Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285755 | 0.85 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2CA2TYR | |
| SCHEMBL13449766 | 0.85 | BACE1 (0.44) | ALDH1A1SMN1; SMN2CA2GABRA1GABRB2 | |
| SCHEMBL15341308 | 0.85 | ALDH1A1 (0.37) | ALDH1A1POLBSMN1; SMN2CA2TYR | |
| SCHEMBL9789782 | 0.85 | GABRA1 (0.42) | ALDH1A1SMN1; SMN2CA2GABRA1GABRB2 | |
| SCHEMBL30413264 | 0.83 | ALDH1A1 (0.48) | ALDH1A1PTPN1POLBHCAR1SMN1; SMN2 | |
| SCHEMBL20962938 | 0.83 | ALDH1A1 (0.48) | ALDH1A1PTPN1POLBHCAR1SMN1; SMN2 | |
| SCHEMBL18925849 | 0.79 | HSP90AA1 (0.41) | ALDH1A1PTPN1CA2GABRA1GABRB2 | |
| Diorcinol SCHEMBL28744720 | 0.78 | ALDH1A1 (0.60) | ALDH1A1PTPN1POLBHCAR1SMN1; SMN2 | |
| Diorcinol SCHEMBL29629136 | 0.78 | ALDH1A1 (0.60) | ALDH1A1PTPN1POLBHCAR1SMN1; SMN2 | |
| SCHEMBL13587591 | 0.77 | PTGS1 (0.53) | ALDH1A1POLBSMN1; SMN2CA2TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127392-A1 | ECKOL DERIVATIVES, METHODS OF SYNTHESIS AND USES THEREOF | Phloronol, Inc. | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127392-A1 | ECKOL DERIVATIVES, METHODS OF SYNTHESIS AND USES THEREOF | MGLL, PNLIP, ECHS1 | ALDH1A1 1648/4885PTPN1 3594/4885POLB 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.