SCHEMBL9790767

SCHEMBL9790767

Cc1scnc1NC(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FDPS P14324 16/20 0.53
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
MMP8 P22894 1/20 0.44
FDFT1 P37268 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167477 0.69 FDPS (1.00) FDPSCA12CA1MMP8FDFT1
SCHEMBL11345143 0.68 L3MBTL1 (0.39)
SCHEMBL20272446 0.68
SCHEMBL9790731 0.67 FDPS (0.51) FDPSCA12CA1MMP8FDFT1
SCHEMBL9790637 0.67 FDPS (0.51) FDPSCA12CA1MMP8FDFT1
SCHEMBL7164309 0.67 FDPS (1.00) FDPSCA12CA1MMP8
SCHEMBL9790635 0.67 FDPS (1.00) FDPSCA12CA1MMP8FDFT1
SCHEMBL9790646 0.66 FDPS (0.97) FDPSFDFT1
SCHEMBL9790756 0.66 FDPS (0.97) FDPSCA12CA1MMP8
SCHEMBL9790600 0.66 FDPS (0.54) FDPSCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5057505-A Treatment of illnesses attributed to calcium metabolism disorders CIBA-GEIGY CORPORATION (US) 1991-10-15 US disclosed