Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 15/20 | 0.51 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790653 | 0.70 | TRPM8 (0.56) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL9790731 | 0.69 | FDPS (0.51) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL22766547 | 0.68 | — | — | |
| SCHEMBL8974849 | 0.68 | FDPS (0.50) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL8167477 | 0.68 | FDPS (1.00) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL9790767 | 0.67 | FDPS (0.53) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL11401437 | 0.66 | FDPS (0.47) | FDPSFDFT1 | |
| SCHEMBL9790674 | 0.64 | FDPS (0.44) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL9819252 | 0.63 | FDPS (0.47) | FDPSFDFT1CA12CA1MMP8 | |
| SCHEMBL11060452 | 0.63 | CA12 (0.53) | FDPSFDFT1CA12CA1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274346-B1 | SUBSTITUTED AMINOMETHANE-DIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | claimed |
| EP-0274346-A1 | Substituted aminomethane-diphosphonic acids | CIBA-GEIGY AG (CH) | 1988-07-13 | — | — | EP | claimed |
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-5057505-A | Treatment of illnesses attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0274346-B1 | SUBSTITUTED AMINOMETHANE-DIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1991-03-06 | — | — | EP | disclosed |
| US-4973576-A | ANTIARTHRITIC AGENTS, TREATMENT OF HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |
| EP-0274346-A1 | Substituted aminomethane-diphosphonic acids | CIBA-GEIGY AG (CH) | 1988-07-13 | — | — | EP | disclosed |