Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9795270 | 0.92 | GNAI3 (0.34) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL9129520 | 0.87 | NAAA (0.38) | GNAI3GNAO1GNAI1NAAATSHR | |
| Fumaric Acid SCHEMBL9795497 | 0.84 | KMT2A (0.33) | GNAI3GNAO1GNAI1BCHEKMT2A | |
| SCHEMBL9129841 | 0.84 | LMNA (0.36) | NAAATSHRBCHEKMT2ALMNA | |
| SCHEMBL9127574 | 0.82 | KMT2A (0.34) | NAAATSHRBCHEKMT2AKDM4E | |
| SCHEMBL3794825 | 0.81 | GNAI3 (0.50) | GNAI3GNAO1GNAI1NAAACHRNB2 | |
| SCHEMBL9795185 | 0.81 | KEAP1 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL9499995 | 0.79 | CYP2D6 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4GRIN1 | |
| SCHEMBL9795256 | 0.79 | HSD11B1 (0.45) | NAAATSHRBCHEKMT2AALDH1A1 | |
| SCHEMBL9795239 | 0.77 | POLB (0.48) | NAAATSHRBCHEKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |