Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795628 | 0.82 | SIGMAR1 (0.45) | KDM4ETDP1 | |
| SCHEMBL11573258 | 0.82 | TDP1 (0.40) | ALDH1A1KDM4ETDP1KMT2APOLB | |
| SCHEMBL9795734 | 0.81 | OGG1 (0.38) | ALDH1A1SMN1; SMN2HPGDKDM4EKMT2A | |
| SCHEMBL9795724 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2 | |
| SCHEMBL9795600 | 0.75 | ALDH1A1 (0.47) | ALDH1A1PLK1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL9795800 | 0.75 | SIGMAR1 (0.38) | ALDH1A1SMN1; SMN2HPGDKDM4ETDP1 | |
| SCHEMBL339416 | 0.74 | ALDH1A1 (0.50) | ALDH1A1PLK1SMN1; SMN2AOC3KDM4E | |
| SCHEMBL9795555 | 0.74 | POLB (0.38) | ALDH1A1HPGDPOLBATM | |
| SCHEMBL9795705 | 0.74 | MAOA (0.38) | ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL13634482 | 0.73 | ALDH1A1 (0.48) | ALDH1A1PLK1SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |