Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795619 | 0.81 | ALDH1A1 (0.41) | KMT2AALDH1A1KEAP1NFE2L2 | |
| SCHEMBL9795637 | 0.78 | MAOA (0.39) | MAOAMAOBSMN1; SMN2KMT2AMMP13 | |
| SCHEMBL9795706 | 0.77 | CYP3A4 (0.41) | SMN1; SMN2KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9795555 | 0.76 | POLB (0.38) | ALDH1A1L3MBTL1KEAP1NFE2L2 | |
| SCHEMBL11573258 | 0.74 | TDP1 (0.40) | KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL9795602 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AALDH1A1KDM4E | |
| SCHEMBL9795734 | 0.73 | OGG1 (0.38) | SMN1; SMN2KMT2AMMP13ALDH1A1KDM4E | |
| SCHEMBL10439130 | 0.72 | SLC9A1 (0.32) | SMN1; SMN2F2KMT2AMMP13ALDH1A1 | |
| SCHEMBL9795628 | 0.72 | SIGMAR1 (0.45) | KDM4E | |
| SCHEMBL9795800 | 0.70 | SIGMAR1 (0.38) | SMN1; SMN2ALDH1A1KDM4EGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023255-A | Triazine derivatives; inhibitors exzyme 5-lipoxygenase | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0388165-A2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |