Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679829 | 0.89 | OPRM1 (0.40) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL2376360 | 0.85 | OPRM1 (0.44) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL2488429 | 0.84 | OPRM1 (0.44) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL4742742 | 0.84 | OPRM1 (0.44) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL2018408 | 0.84 | OPRM1 (0.44) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30082837 | 0.83 | OPRM1 (0.43) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL2457947 | 0.80 | LMNA (0.36) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL6674978 | 0.79 | KDM4E (0.49) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27535166 | 0.78 | KDM4E (0.48) | OPRM1OPRK1KDM4EALDH1A1LMNA | |
| SCHEMBL159474 | 0.76 | TAS1R3 (0.37) | OPRM1OPRK1LMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |