Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9799390 | 0.68 | CYP3A4 (0.43) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10583553 | 0.68 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9799541 | 0.68 | PTGS2 (0.39) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9831867 | 0.68 | OPRM1 (0.40) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9833168 | 0.68 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9832757 | 0.68 | TUBB4A (0.38) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9799289 | 0.67 | OPRM1 (0.43) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9799232 | 0.66 | OPRM1 (0.40) | L3MBTL1ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL9799522 | 0.66 | TUBB4A (0.39) | L3MBTL1CYP3A4SMN1; SMN2BRD4CYP1A2 | |
| SCHEMBL9799313 | 0.65 | TUBB4A (0.38) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |