Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.38 |
| ▸ | TUBB | P07437 | 5/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833083 | 0.83 | OPRM1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9833569 | 0.82 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL9799390 | 0.78 | CYP3A4 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9833086 | 0.77 | NPC1 (0.38) | L3MBTL1ALDH1A1HPGDCYP3A4MEN1 | |
| SCHEMBL9831386 | 0.76 | MAPT (0.45) | L3MBTL1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9832269 | 0.73 | MAPT (0.36) | ALDH1A1KDM4EHPGDCYP3A4MEN1 | |
| SCHEMBL27272132 | 0.68 | ESR1 (0.32) | ESR1 | |
| SCHEMBL11162193 | 0.68 | HTR2A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12963223 | 0.68 | AR (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10583553 | 0.68 | L3MBTL1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0297782-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |