Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799796 | 0.89 | ALDH1A1 (0.40) | CYP19A1CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9799541 | 0.86 | PTGS2 (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9833168 | 0.82 | L3MBTL1 (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9833569 | 0.81 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9799824 | 0.81 | NPC1 (0.35) | CYP1A2CYP2C9CYP2C19L3MBTL1MEN1 | |
| SCHEMBL9799232 | 0.79 | OPRM1 (0.40) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9799522 | 0.79 | TUBB4A (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9799815 | 0.78 | L3MBTL1 (0.35) | L3MBTL1MAPTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9799390 | 0.70 | CYP3A4 (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10423292 | 0.69 | KDM4E (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298703-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0298703-A1 | A thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-01-11 | — | — | EP | disclosed |