Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054987 | 0.78 | TRPA1 (0.35) | TRPA1ALDH1A1 | |
| SCHEMBL13808647 | 0.76 | TRPA1 (0.41) | TRPA1ALDH1A1MGLL | |
| SCHEMBL24575773 | 0.72 | GSK3A (0.38) | ALDH1A1GSK3AGSK3BMGLL | |
| SCHEMBL13781605 | 0.70 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL19291609 | 0.69 | MAOA (0.35) | TRPA1 | |
| SCHEMBL18671660 | 0.69 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL15160718 | 0.69 | TRPA1 (0.40) | TRPA1ALDH1A1 | |
| SCHEMBL13531726 | 0.67 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL20897220 | 0.67 | TRPA1 (0.39) | TRPA1ALDH1A1 | |
| SCHEMBL19336228 | 0.67 | ALDH1A1 (0.42) | TRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154344-A1 | 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022270541-A1 | NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE PHOTOSENSITIVE POLYMER, CURED FILM, AND SEMICONDUCTOR DEVICE | 住友ベークライト株式会社 | 2022-12-29 | — | — | WO | disclosed |
| EP-3359544-B1 | NOVEL MODIFIED MACROCYCLIC COMPOUNDS | Bayer Pharma AG (DE) | 2020-08-12 | — | — | EP | disclosed |
| EP-2265092-B1 | Electroluminescent device | UDC IRELAND LTD (IE) | 2018-03-14 | — | — | EP | disclosed |
| EP-2041200-B1 | NOVEL ELECTROLUMINESCENT POLYMERS FOR ELECTRONIC APPLICATIONS | UDC IRELAND LTD (IE) | 2018-03-07 | — | — | EP | disclosed |
| WO-2017060167-A1 | NOVEL MODIFIED MACROCYCLIC COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | WO | disclosed |
| US-8969003-B2 | Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use | ELITECH HOLDING B.V. (NL) | 2015-03-03 | — | — | US | disclosed |
| US-20130261014-A1 | FUNCTIONALIZED 3-ALKYNYL PYRAZOLOPYRIMIDINE ANALOGUES AS UNIVERSAL BASES AND METHODS OF USE | ELITECHGROUP MDX LLC | 2013-10-03 | — | — | US | disclosed |
| US-20130252975-A1 | NOVEL ROCK INHIBITORS | AMAKEM NV (BE) | 2013-09-26 | — | — | US | disclosed |
| US-20130252975-A1 | NOVEL ROCK INHIBITORS | AMAKEM NV (BE) | 2013-09-26 | — | — | US | disclosed |
| US-5041663-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-5032169-A | Antidotes for herbicides | CIBA-GEIGY CORPORATION (US) | 1991-07-16 | — | — | US | disclosed |
| US-4759789-A | Treating locus of plant before or during application of herbicide with oxime ether compound | CIBA-GEIGY CORPORATION (US) | 1988-07-26 | — | — | US | disclosed |
| US-4566901-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261014-A1 | FUNCTIONALIZED 3-ALKYNYL PYRAZOLOPYRIMIDINE ANALOGUES AS UNIVERSAL BASES AND METHODS OF USE | NUDT1, ADAR, DPYD | TRPA1 2297/4885ALDH1A1 669/4885GSK3A 4856/4885 |
| US-20130252975-A1 | NOVEL ROCK INHIBITORS | ROCK1, ROCK2, CIT | TRPA1 4657/4885ALDH1A1 3675/4885GSK3A 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.