SCHEMBL7587882

SCHEMBL7587882

O=C(c1ccccc1)C1(c2ccccc2)CC=CCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.40
LMNA P02545 3/20 0.35
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA5A P35218 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA13 Q8N1Q1 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
F2 P00734 1/20 0.33
AKR1C1 Q04828 1/20 0.33
CES2 O00748 3/20 0.32
CES1 P23141 3/20 0.32
TSHR P16473 2/20 0.32
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8765171 0.79 LMNA (0.41) HDAC4LMNACA2CA4CA12
SCHEMBL9800616 0.78 LMNA (0.38) HDAC4LMNACA2CA4CA12
SCHEMBL6326779 0.72 LMNA (0.36) LMNACA2CA4CA12CA1
SCHEMBL14453309 0.71 LMNA (0.35) LMNAF2AKR1C1CES2CES1
SCHEMBL10528811 0.70 GLS (0.42) LMNAF2CES2CES1TSHR
SCHEMBL9718669 0.70 AKR1C1 (0.39) HDAC4LMNAAKR1C1TSHRALDH1A1
SCHEMBL28178056 0.69 CA2 (0.44) HDAC4LMNACA2CA4CA12
SCHEMBL761526 0.69 CES2 (0.47) CES2CES1TSHRMAPTNPC1
SCHEMBL10415978 0.69 MAPT (0.41) LMNAALDH1A1OPRM1OPRL1MAPT
SCHEMBL10414509 0.69 LMNA (0.43) LMNACA2CA1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020121631-A1 Reactive monomer; reactive oligomeric resin; and aqueous polymer emulsion; provides an overprint varnish that can be applied in-line over a conventional lithographic ink. GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-09-05 US disclosed
US-5670006-A COATING A SUBSTRATE WITH A LAYER OF INTERPENETRATING NETWORK OF POLYMERIZED EPOXY MONOMERS AND ARYLATE MONOMERS, FREE RADICAL INITIATOR AND CATIONIC INITIATORS, CURING, FIXING CURED LAYER TO VIBRATING ARTICLE, REMOVING THE RELEASE LINER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-23 US disclosed
EP-0621931-B1 VIBRATION DAMPING CONSTRUCTIONS USING ACRYLATE-CONTAINING DAMPING MATERIALS MINNESOTA MINING & MFG (US) 1997-07-30 EP disclosed
EP-0476822-B1 Energy curable pressure-sensitive compositions MINNESOTA MINING & MFG (US) 1997-03-05 EP disclosed
US-5521227-A ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-28 US disclosed
EP-0526463-B1 ENERGY CURABLE CATIONICALLY AND FREE-RADICALLY POLYMERIZABLE PRESSURE-SENSITIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1996-05-22 EP disclosed
EP-0623152-B1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME MINNESOTA MINING & MFG (US) 1996-01-31 EP disclosed
EP-0521112-B1 POLYMERIC MIXTURES AND PROCESS THEREFOR MINNESOTA MINING & MFG (US) 1996-01-03 EP disclosed
US-5462797-A Photoinitiator system of an organometallic complex and free radical catalyst MINNEAPOLIS MINING AND MANUFACTURING COMPANY (US) 1995-10-31 US disclosed
US-5399637-A Energy-polymerizable adhesive, coating, and film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
EP-0623152-A1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME. MINNESOTA MINING & MFG (US) 1994-11-09 EP disclosed
US-5310840-A Energy-polymerizable adhesive, coating and film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-10 US disclosed
US-5262232-A Interpenetrating polymer network of acrylate and epoxy, high temperature use MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
US-5252694-A Curable epoxy-acrylate mixture, catalyst system, peroxide, and alcohol MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-12 US disclosed
EP-0563057-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-06 EP disclosed
US-5238744-A Tough polymeric mixtures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US disclosed
WO-1993015125-A1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-05 WO disclosed
WO-1992011332-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-09 WO disclosed
EP-0476822-A2 Energy curable pressure-sensitive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-25 EP disclosed
US-4707432-A PROTECTIVE COATINGS, IMAGES CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed