Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29113876 | 0.87 | DHFR (0.44) | GABRA1GABRB2DHFRHMGCRPRKCI | |
| SCHEMBL13981267 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4EPDE10AHMGCR | |
| SCHEMBL854703 | 0.81 | SHBG (0.45) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL11612512 | 0.79 | CA1 (0.54) | GABRA1GABRB2ALDH1A1SHBGMAOA | |
| SCHEMBL1024995 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL5161523 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4EPDE10ATP53 | |
| SCHEMBL12209717 | 0.79 | ALDH1A1 (0.40) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL6985327 | 0.78 | THRB (0.56) | GABRA1GABRB2ALDH1A1GAAKDM4E | |
| SCHEMBL225765 | 0.78 | SHBG (0.52) | ALDH1A1SHBGDHFRMAOAESR1 | |
| SCHEMBL1021110 | 0.78 | SHBG (0.52) | GABRA1GABRB2ALDH1A1SHBGDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116409-B1 | FUNGICIDAL ANILINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4647584-A | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4647583-A | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4517005-A | Aminophenol urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0116409-A2 | Fungicidal aniline derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-22 | — | — | EP | disclosed |
| US-4007212-A | Novel amide compounds | POLAROID CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |