Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095681 | 0.92 | PDE10A (0.41) | SHBGALDH1A1HIF1AHSD17B10KDM4E | |
| SCHEMBL27611624 | 0.90 | SHBG (0.39) | SHBGALDH1A1HIF1AHSD17B10KDM4E | |
| SCHEMBL14095698 | 0.86 | AMY1A (0.42) | SHBGALDH1A1HIF1AHSD17B10KDM4E | |
| SCHEMBL7452287 | 0.86 | ALDH1A1 (0.44) | SHBGALDH1A1HIF1AHSD17B10KDM4E | |
| SCHEMBL12209717 | 0.84 | ALDH1A1 (0.40) | SHBGALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6651758 | 0.84 | ALDH1A1 (0.35) | SHBGALDH1A1HIF1AHSD17B10KDM4E | |
| SCHEMBL10952937 | 0.83 | SHBG (0.37) | SHBGALDH1A1HIF1AKDM4ELMNA | |
| SCHEMBL9800893 | 0.81 | GABRA1 (0.38) | SHBGALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL655476 | 0.80 | CA1 (0.58) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL9115480 | 0.79 | ALOX5 (0.48) | SHBGALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473025-B1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | OREAL (FR) | 2012-03-28 | — | — | EP | claimed |
| EP-1493426-B1 | Dyeing composition comprising a developer, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | OREAL (FR) | 2009-08-12 | — | — | EP | claimed |
| US-7306630-B2 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2007-12-11 | — | — | US | claimed |
| US-20050028302-A1 | Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | L'OREAL S.A. (FR) | 2005-02-10 | — | — | US | claimed |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | L'OREAL S.A. (FR) | 2005-01-06 | — | — | US | claimed |
| EP-1493426-A1 | Dyeing composition comprising a developer, 2-chloro-6-methyl-3-aminophenol and 3-methyl-5-pyrazolone | L'OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| US-20040216245-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a para-aminophenol, methods and uses | L'OREAL (FR) | 2004-11-04 | — | — | US | claimed |
| EP-1473025-A1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | L'OREAL (FR) | 2004-11-03 | — | — | EP | claimed |
| US-9980893-B2 | Dye composition comprising a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound | L'OREAL (FR) | 2018-05-29 | — | — | US | disclosed |
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'OREAL (FR) | 2018-05-24 | — | — | US | disclosed |
| EP-2791116-B1 | COUPLER WITH 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINE STRUCTURE, DYEING COMPOSITION COMPRISING SAME, PROCESSES AND USES | OREAL (FR) | 2018-05-16 | — | — | EP | disclosed |
| US-20170327690-A1 | CATIONIC BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | OREAL (FR) | 2017-11-16 | — | — | US | disclosed |
| EP-3233812-A1 | CATIONIC BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'Oréal (FR) | 2017-10-25 | — | — | EP | disclosed |
| EP-3177615-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'Oréal (FR) | 2017-06-14 | — | — | EP | disclosed |
| EP-1473025-A1 | Dyeing composition containing 2-chloro-6-methyl-3-aminophenol and an associative polymer | L'OREAL (FR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1473024-A1 | Dyeing composition comprising 2-chloro 6-methyl 3-amino phenol | L'OREAL (FR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1229891-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-1222161-A1 | AMINOPHENOL DERIVATIVES AND THE USE THEREOF IN OXIDATIVE HAIR DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001034105-A1 | AGENT FOR COLOURING KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001030743-A1 | AMINOPHENOL DERIVATIVES AND THE USE THEREOF IN OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141922-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | XDH, KRT18, CYC1 | SHBG 1455/4885ALDH1A1 1230/4885HIF1A 1562/4885 |
| US-20040216245-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a para-aminophenol, methods and uses | KRT18, CDC73, NUP205 | SHBG 438/4885ALDH1A1 714/4885HIF1A 4285/4885 |
| US-20050000039-A1 | Composition comprising at least one coupler chosen from 2-chloro-6-methyl-3-aminophenol and addition salts thereof, at least one oxidation base, and at least one associative polymer comprising at least one C8-C30 fatty chain | FABP4, KRT18, S100A10 | SHBG 1106/4885ALDH1A1 679/4885HIF1A 4436/4885 |
| US-20170327690-A1 | CATIONIC BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | TYR, CAT, CYC1 | SHBG 2446/4885ALDH1A1 199/4885HIF1A 993/4885 |
| US-20050028302-A1 | Dye composition comprising at least one oxidation base, 2-chloro-6-methyl-3-aminophenol and 3-methyl-1-phenyl-5-pyrazolone | KRT18, COX5A, COX5B | SHBG 830/4885ALDH1A1 182/4885HIF1A 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.