Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806566 | 0.82 | MEN1 (0.66) | KMT2AMEN1ALDH1A1TP53P2RX1 | |
| SCHEMBL3768399 | 0.82 | RAB9A (0.63) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL4372468 | 0.82 | P2RX1 (0.71) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL9806572 | 0.81 | LMNA (0.65) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL28771223 | 0.81 | TERT (0.84) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL6793906 | 0.79 | MEN1 (0.93) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL11675529 | 0.79 | MEN1 (1.00) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL29800565 | 0.79 | MEN1 (0.93) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL9400341 | 0.78 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL29473480 | 0.78 | ALDH1A1 (0.70) | KMT2AMEN1ALDH1A1CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423163-A1 | OXIDATIVE HAIR DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-04-24 | — | — | EP | disclosed |
| WO-1990000047-A1 | OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-01-11 | — | — | WO | disclosed |