Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 11/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503269 | 0.83 | NPBWR1 (0.35) | NPBWR1NPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9806729 | 0.73 | NPBWR1 (0.33) | NPBWR1NPSR1LMNASMN1; SMN2SLC6A2 | |
| SCHEMBL9504425 | 0.70 | NPBWR1 (0.35) | NPBWR1NPSR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11464658 | 0.68 | SLC6A4 (0.42) | NPBWR1SMN1; SMN2ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9503278 | 0.67 | THRB (0.59) | — | |
| SCHEMBL9501824 | 0.66 | LMNA (0.31) | NPBWR1NPSR1LMNASMN1; SMN2MCHR1 | |
| Sulazuril SCHEMBL8602617 | 0.66 | PTGS2 (0.38) | — | |
| SCHEMBL11460774 | 0.65 | PDE7A (0.46) | NPSR1LMNASMN1; SMN2ALDH1A1SLC6A2 | |
| SCHEMBL11647493 | 0.65 | GABRP (0.43) | NPBWR1LMNASMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL11471382 | 0.65 | SLC6A4 (0.40) | NPBWR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215354-B1 | SUBSTITUTED 2-PHENYL-HEXAHYDRO-1,2,4-TRIAZINE-3,5-DIONES, PROCESS FOR THEIR PREPARATION, PRODUCTS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-24 | — | — | EP | disclosed |
| US-4782056-A | COCCIDIOSTATICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| EP-0215354-A2 | Substituted 2-phenyl-hexahydro-1,2,4-triazine-3,5-diones, process for their preparation, products containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-25 | — | — | EP | disclosed |