Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807385 | 0.82 | ALDH1A1 (0.53) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4859122 | 0.78 | MEN1 (0.69) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL13840640 | 0.77 | CYP1A2 (0.57) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL9807405 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1GPR35 | |
| SCHEMBL28104443 | 0.71 | HTT (0.54) | CYP1A2CYP2C9HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL16701937 | 0.71 | HSD17B1 (0.51) | SMN1; SMN2ALDH1A1GPR35TDP1TSHR | |
| SCHEMBL12644251 | 0.71 | MAOB (0.59) | CYP1A2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6723884 | 0.70 | LMNA (0.66) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13840638 | 0.70 | CA2 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL10934571 | 0.69 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994545-A | Polyetherimide | ETHYL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4990627-A | Polyetherimides and their production | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |