Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807385 | 0.89 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPTTDP1MEN1 | |
| SCHEMBL9807428 | 0.84 | TSHR (0.50) | ALDH1A1GPR35GSK3AGSK3BMAPT | |
| SCHEMBL2036487 | 0.80 | ALDH1A1 (0.65) | ALDH1A1GPR35MAPTTDP1MEN1 | |
| SCHEMBL16712983 | 0.77 | ESR2 (0.56) | ALDH1A1GPR35MAPTTDP1MEN1 | |
| SCHEMBL16701937 | 0.77 | HSD17B1 (0.51) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL9807400 | 0.76 | CYP1A2 (0.45) | ALDH1A1GPR35MAPTTDP1MEN1 | |
| SCHEMBL6723884 | 0.75 | LMNA (0.66) | ALDH1A1GPR35MAPTMEN1KMT2A | |
| SCHEMBL12644251 | 0.74 | MAOB (0.59) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL13552108 | 0.74 | KMT2A (0.59) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL4541837 | 0.73 | GPR35 (0.47) | ALDH1A1GPR35GSK3AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994545-A | Polyetherimide | ETHYL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4990627-A | Polyetherimides and their production | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |