SCHEMBL9808445

SCHEMBL9808445

N#Cc1ccc2sc(N)nc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.51
CYP2C9 P11712 1/20 0.51
PIK3CD O00329 1/20 0.50
PIK3CA P42336 1/20 0.50
PIK3CB P42338 1/20 0.50
PIK3CG P48736 1/20 0.50
CYP2C19 P33261 1/20 0.49
PPARA Q07869 1/20 0.48
APP P05067 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
AXL P30530 1/20 0.43
GFER P55789 1/20 0.43
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2001976 0.86 APP (0.63) CYP3A4CYP2C9PIK3CDPIK3CAPIK3CB
SCHEMBL507628 0.80 PPARA (0.49) PPARAAPPALDH1A1MAPTGAA
SCHEMBL1748230 0.79 PPARA (0.48) PPARAAPPSMN1; SMN2ALDH1A1RAB9A
SCHEMBL7380470 0.79 SMN1; SMN2 (0.52) PPARAAPPSMN1; SMN2ALDH1A1TP53
SCHEMBL12298168 0.79 PPARA (0.48) CYP2C9PPARAAPPALDH1A1MAPT
SCHEMBL1997208 0.79 PPARA (0.48) CYP2C9PPARAAPPALDH1A1MAPT
SCHEMBL30602948 0.79 PPARA (0.48) CYP2C9PPARAAPPALDH1A1MAPT
SCHEMBL24963247 0.78 LOXL2 (0.59) CYP3A4CYP2C9CYP2C19PPARAAPP
SCHEMBL2140314 0.78 IDO1 (0.59) PPARAAPPSMN1; SMN2ALDH1A1RAB9A
SCHEMBL18273030 0.77 CYP3A4 (0.41) CYP3A4CYP2C9CYP2C19APPSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114960229-A Tent cloth dyeing process 圣山集团有限公司 2022-08-30 CN claimed
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INST NAT SANTE RECH MED (FR) 2025-12-18 US disclosed
EP-4460500-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 2024-11-13 EP disclosed
CN-118660885-A Norbornene analogs and their use as potentiators of antitubercular drugs 国家医疗保健研究所 2024-09-17 CN disclosed
WO-2023131649-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2023-07-13 WO disclosed
CN-116173204-A Glutathione activated co-assembled nano probe and preparation method and application thereof 南京大学 2023-05-30 CN disclosed
CN-114960229-A Tent cloth dyeing process 圣山集团有限公司 2022-08-30 CN disclosed
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof Shanghai De Novo Pharmatech Co., Ltd. (CN) 2019-02-12 US disclosed
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF Shanghai De Novo Pharmatech Co., Ltd. (CN) 2018-01-25 US disclosed
EP-0169459-B1 AZO DYES BAYER AG (DE) 1991-05-15 EP disclosed
EP-0169459-A2 Azo dyes BAYER AG (DE) 1986-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10202388-B2 Fused-ring compounds, pharmaceutical composition and uses thereof IDO1, IDO2, TDO2 CYP3A4 72/4885CYP2C9 49/4885PIK3CD 1209/4885
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS BBOX1, NDUFB6, NDUFB5 CYP3A4 343/4885CYP2C9 806/4885PIK3CD 3384/4885
US-20180022752-A1 FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF IDO1, IDO2, TDO2 CYP3A4 72/4885CYP2C9 49/4885PIK3CD 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.