Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808912 | 0.85 | LMNA (0.54) | HCAR3LMNAMAPTALDH1A1GAA | |
| SCHEMBL11656952 | 0.80 | MAPT (0.54) | HCAR3MAPTALDH1A1POLBHTT | |
| SCHEMBL9808943 | 0.77 | GAA (0.48) | HCAR3LMNAMAPTALDH1A1GAA | |
| SCHEMBL10507609 | 0.76 | GAA (0.49) | LMNAMAPTALDH1A1GAAPOLB | |
| SCHEMBL9808908 | 0.75 | LMNA (0.50) | HCAR3LMNAMAPTALDH1A1GAA | |
| SCHEMBL162875 | 0.74 | KAT2B (0.60) | HCAR3LMNAMAPTALDH1A1HTT | |
| SCHEMBL9808913 | 0.74 | VCAM1 (0.51) | LMNAMAPTALDH1A1GAAHTT | |
| SCHEMBL11197700 | 0.74 | MAPK1 (0.50) | LMNAMAPTALDH1A1POLBHTT | |
| SCHEMBL9808904 | 0.74 | TDP1 (0.51) | LMNAMAPTALDH1A1POLBKMT2A | |
| SCHEMBL9808919 | 0.73 | ALDH1A1 (0.54) | LMNAMAPTALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | claimed |
| US-4985463-A | Aminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-01-15 | — | — | US | disclosed |
| US-4956007-A | Nitraminodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them | RICHTER GEDEON VEGYESZETI GYOR RT. (HU) | 1990-09-11 | — | — | US | disclosed |
| US-4831194-A | Process for the preparation of nitrodiaryl sulfoxides | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1989-05-16 | — | — | US | disclosed |
| US-4710323-A | Nitrodiaryl sulfoxide derivatives, process for their preparation and pharmaceutical and pesticidal compositions containing them as active ingredient | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1987-12-01 | — | — | US | disclosed |