Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298267 | 0.80 | SLC18A3 (0.57) | KMT2ATSHRDRD2SLC18A3MEN1 | |
| SCHEMBL9811419 | 0.79 | CCR2 (0.40) | DRD2SLC18A3FDPSKCNA3 | |
| SCHEMBL9811461 | 0.78 | HRH3 (0.46) | DRD2SLC18A3FDPSKCNA3 | |
| SCHEMBL9811498 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ALMNATSHR | |
| SCHEMBL6221175 | 0.75 | SLC18A3 (0.55) | KMT2ATSHRCHRM2CHRM4CHRM5 | |
| SCHEMBL6223991 | 0.75 | DRD2 (0.57) | KMT2ADRD2DRD4DRD3MEN1 | |
| SCHEMBL9811433 | 0.75 | DRD2 (0.46) | DRD2DRD4DRD3SLC18A3KCNA3 | |
| SCHEMBL9811522 | 0.75 | DRD2 (0.48) | DRD2DRD3SLC18A3 | |
| SCHEMBL9811541 | 0.75 | DRD4 (0.50) | ALDH1A1DRD2DRD4DRD3FDPS | |
| SCHEMBL9811477 | 0.74 | FDPS (0.49) | ALDH1A1MAPTLMNASLC18A3FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272208-B1 | AROMATICALLY SUBSTITUTED AZACYCLO-ALKYLALKANEDIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1991-06-12 | — | — | EP | disclosed |
| US-4871720-A | Aromatically substituted azacycloalkyl-alkanediphosphonic acids useful for the treatment of illnesses that can be attributed to calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0272208-A1 | Aromatically substituted azacyclo-alkylalkanediphosphonic acids | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |