Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645954 | 0.81 | ADRB1 (0.55) | HTR7HTR1AHTR2BHTR6ALDH1A1 | |
| SCHEMBL3483001 | 0.81 | ADRB1 (0.55) | HTR7HTR1ATP53HTR2BHTR6 | |
| SCHEMBL6094315 | 0.81 | QDPR (0.39) | KDM4EALDH1A1MAPTSIGMAR1HTR3A | |
| SCHEMBL739058 | 0.80 | SIGMAR1 (0.52) | HTR7HTR1ATP53HTR2BHTR6 | |
| SCHEMBL3537094 | 0.78 | PLD1 (0.57) | ALDH1A1SLC6A4 | |
| SCHEMBL6956749 | 0.78 | KDM4E (0.43) | KDM4ETP53POLB | |
| SCHEMBL2410875 | 0.77 | ADRB1 (0.59) | HTR7HTR1AHTR2BHTR6POLB | |
| SCHEMBL3482920 | 0.75 | HTR2C (0.38) | HTR7HTR1AKDM4EHTR2BALDH1A1 | |
| SCHEMBL22159394 | 0.74 | BPTF (0.38) | HTR7HTR1AHTR2BHTR6BPTF | |
| SCHEMBL6094131 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTGFERMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608619-B2 | Substituted oxazole compounds with analgesic activity | GRUENENTHAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20020128231-A1 | Aryl-indane compounds | EASTMAN CHEMICAL COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002030915-A2 | ARYL-INDANE COMPOUNDS FOR USE AS INHIBITORS OF P-GLYCOPROTEIN MEDIATED TRANSPORT | AVLAN LIMITED (GB) | 2002-04-18 | — | — | WO | disclosed |
| US-4338453-A | Aminoalkyl-1,2,4-triazoles | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069330-A1 | Substituted Oxazole Compounds with Analgesic Activity | OPRK1, OPRD1, OPRM1 | HTR7 195/4885HTR1A 278/4885KDM4E 2740/4885 |
| US-20020128231-A1 | Aryl-indane compounds | ABCB1, ABCC1, ABCG2 | HTR7 2496/4885HTR1A 3276/4885KDM4E 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.