SCHEMBL9814030

SCHEMBL9814030

COCCOC(=O)N=C=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ADORA2A P29274 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11870755 0.89
SCHEMBL11691210 0.81 TSHR (0.37) TSHRADORA2AALDH1A1
SCHEMBL11851237 0.80
SCHEMBL11870751 0.77
SCHEMBL8544588 0.77 ALDH1A1 (0.50) TSHRALDH1A1
SCHEMBL15851249 0.77 TSHR (0.43) TSHRADORA2AALDH1A1
SCHEMBL1142535 0.77 TSHR (0.43) TSHRADORA2AALDH1A1
SCHEMBL1142533 0.77 TSHR (0.43) TSHRADORA2AALDH1A1
SCHEMBL9124160 0.76 THRB (0.35) TSHR
SCHEMBL5821261 0.75 NAAA (0.48) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102407-A1 TREATMENT METHODS KHACHIGIAN LEVON MICHAEL (AU) 2026-04-16 US disclosed
US-20240050444-A1 TREATMENT METHODS VASCULAR THERAPEUTICS PTY LTD (AU) 2024-02-15 US disclosed
EP-4117655-A1 TREATMENT METHODS Khachigian, Levon, Michael (AU) 2023-01-18 EP disclosed
WO-2021184059-A1 TREATMENT METHODS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2021-09-23 WO disclosed
EP-0230224-B1 PROCESS FOR THE PREPARATION OF ALCOXYCARBONYL ISOCYANATES BAYER AG (DE) 1991-07-17 EP disclosed
US-4777283-A Process for the preparation of alkoxycarbonyl isocyanates BAYER AKTIENGESELLSCHAFT (DE) 1988-10-11 US disclosed
EP-0230224-A2 Process for the preparation of alcoxycarbonyl isocyanates BAYER AG (DE) 1987-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240050444-A1 TREATMENT METHODS FOSB, FOS, VCAM1 TSHR 2518/4885ADORA2A 3287/4885ALDH1A1 2600/4885
US-20260102407-A1 TREATMENT METHODS FOSB, VCAM1, FOS TSHR 1510/4885ADORA2A 2719/4885ALDH1A1 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.