Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981619 | 0.91 | LMNA (0.38) | SMN1; SMN2POLBLMNALOXL2KDM4E | |
| Bromide SCHEMBL29450513 | 0.89 | LMNA (0.37) | SMN1; SMN2POLBLMNALOXL2KDM4E | |
| Hydrochloric Acid SCHEMBL1289973 | 0.89 | LMNA (0.37) | SMN1; SMN2POLBLMNALOXL2KDM4E | |
| Sulfuric Acid SCHEMBL1289861 | 0.83 | CA1 (0.36) | SMN1; SMN2POLBLMNALOXL2KDM4E | |
| Trifluoroacetic Acid SCHEMBL13519111 | 0.79 | MCL1 (0.38) | MMP2SMN1; SMN2POLBALDH1A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL28343191 | 0.78 | ALDH1A1 (0.39) | MMP2SMN1; SMN2POLBLMNAKDM4E | |
| Trifluoroacetic Acid SCHEMBL11288932 | 0.76 | ITGB1 (0.38) | MMP2LMNAKDM4EALDH1A1CACNA1H | |
| Trifluoroacetic Acid SCHEMBL11688514 | 0.76 | CA2 (0.40) | MMP2KDM4EMEN1KMT2AGLRA1 | |
| Trifluoroacetic Acid SCHEMBL17727570 | 0.75 | KDM1A (0.33) | MMP2 | |
| Trifluoroacetic Acid SCHEMBL7711992 | 0.75 | NPC1 (0.33) | MMP2SMN1; SMN2POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150575-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2023-08-09 | — | — | EP | disclosed |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2023-03-28 | — | — | US | disclosed |
| US-10745344-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190144374-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | CORTEVA AGRISCIENCE LLC | 2019-05-16 | — | — | US | disclosed |
| US-20190144373-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | CORTEVA AGRISCIENCE LLC | 2019-05-16 | — | — | US | disclosed |
| US-10202332-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2019-02-12 | — | — | US | disclosed |
| EP-3150575-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E. I. du Pont de Nemours and Company (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2621894-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2016-11-16 | — | — | EP | disclosed |
| CN-103124721-B | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | DU PONT | 2015-06-03 | — | — | CN | disclosed |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-10 | — | — | US | disclosed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| CN-103124721-A | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | DU PONT | 2013-05-29 | — | — | CN | disclosed |
| US-8383659-B2 | Isoxazoline derivatives as pesticides | NOVARTIS AG (CH) | 2013-02-26 | — | — | US | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ELANCO TIERGESUNDHEIT AG (CH) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202332-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
| US-10745344-B2 | Method for preparing 2-amino-N-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ACHE, VDAC1, VDAC2 | MMP2 867/4885SMN1; SMN2 648/4885POLB 2491/4885 |
| US-20190144374-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
| US-20190144373-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | MMP2 3483/4885SMN1; SMN2 433/4885POLB 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.