SCHEMBL981835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL981834	0.90	LMNA (0.39)	CNR2CNR1KDM4EMEN1LMNA
	SCHEMBL981797	0.79	ESR1 (0.33)	KDM4EMAPK1HTTESR1
	SCHEMBL10095826	0.79	NSD2 (0.32)	LMNAESR1NSD2DOT1LAS3MT
	SCHEMBL981767	0.79	KDM4E (0.43)	KDM4EMEN1LMNAMAPTPABPC1
	SCHEMBL10193509	0.79	PDE1C (0.37)	CNR1
	SCHEMBL10096278	0.78	LMNA (0.38)	KDM4EMEN1LMNAMAPTPABPC1
	SCHEMBL14466447	0.78	ESR1 (0.36)	KDM4EMEN1LMNAMAPTHTT
	SCHEMBL10095819	0.77	PDE5A (0.39)	CNR2CNR1KDM4EMEN1LMNA
	SCHEMBL13152817	0.77	LMNA (0.41)	CNR2CNR1KDM4ELMNAMAPK1
	SCHEMBL10095879	0.77	LMNA (0.37)	KDM4EMEN1LMNAMAPTPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.