SCHEMBL981834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL981835	0.90	CNR2 (0.37)	LMNACNR2CNR1GRM2KDM4E
	SCHEMBL981767	0.89	KDM4E (0.43)	LMNATP53KDM4EMAPK1HTT
	SCHEMBL10193509	0.89	PDE1C (0.37)	CNR1TP53PADI4AKR1C3
	SCHEMBL10095826	0.89	NSD2 (0.32)	LMNAPDE4APADI4
	SCHEMBL10096278	0.89	LMNA (0.38)	LMNATP53KDM4EMAPK1HTT
	SCHEMBL10095819	0.88	PDE5A (0.39)	LMNACNR2CNR1TP53KDM4E
	SCHEMBL13152817	0.88	LMNA (0.41)	LMNACNR2CNR1TP53KDM4E
	SCHEMBL10095879	0.87	LMNA (0.37)	LMNATP53GRM2KDM4EMAPK1
	SCHEMBL14466447	0.87	ESR1 (0.36)	LMNAKDM4EHTTMEN1MAPT
	SCHEMBL12106336	0.85	GRM2 (0.34)	LMNAGRM2KDM4EMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.