Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819084 | 0.88 | MAPT (0.51) | TRPV1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9818887 | 0.85 | IDO1 (0.47) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL9818923 | 0.84 | MAPT (0.47) | TRPV1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9819070 | 0.83 | KCNMA1 (0.50) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9819203 | 0.83 | PDK1 (0.50) | ALDH1A1MAPTMEN1KMT2AIDO1 | |
| SCHEMBL9818946 | 0.83 | ABCG2 (0.50) | TRPV1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9818865 | 0.83 | ABCG2 (0.50) | TRPV1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9819345 | 0.82 | MAPT (0.54) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9819414 | 0.80 | LMNA (0.45) | TRPV1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9819349 | 0.78 | MEN1 (0.50) | TRPV1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |