Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 9/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819189 | 0.87 | SRD5A1 (0.44) | KMT2AOPRM1SRD5A1SRD5A2OPRK1 | |
| SCHEMBL9819217 | 0.81 | ALOX5 (0.45) | BCL2A1MAPTHTR1A | |
| SCHEMBL9819344 | 0.79 | DRD2 (0.48) | KMT2AMEN1MAPTSRD5A1POLB | |
| SCHEMBL9819448 | 0.77 | DRD2 (0.52) | KMT2AMEN1MAPTALOX12 | |
| SCHEMBL9819424 | 0.76 | BCL2A1 (0.49) | KMT2ABCL2A1MEN1MAPTALOX12 | |
| SCHEMBL9819272 | 0.75 | SLC6A2 (0.56) | KMT2AMEN1 | |
| SCHEMBL11634811 | 0.75 | BCL2A1 (0.42) | KMT2ABCL2A1MEN1MAPTALOX12 | |
| SCHEMBL2193401 | 0.74 | KMT2A (0.47) | KMT2AMEN1MAPTALOX12OPRM1 | |
| SCHEMBL9819277 | 0.74 | HSD17B10 (0.44) | KMT2AMEN1MAPTSRD5A1HTR1A | |
| SCHEMBL9819263 | 0.74 | PKM (0.50) | KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |