Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819213 | 0.81 | KMT2A (0.43) | HTR1ABCL2A1MAPT | |
| SCHEMBL24608458 | 0.77 | KDM4E (0.36) | — | |
| SCHEMBL29751165 | 0.77 | KDM4E (0.36) | — | |
| SCHEMBL6418503 | 0.76 | MEN1 (0.59) | HSD11B1MAPT | |
| SCHEMBL9819344 | 0.75 | DRD2 (0.48) | ALOX5HSD11B1MAPT | |
| SCHEMBL9819272 | 0.74 | SLC6A2 (0.56) | HTR2AHTR2C | |
| SCHEMBL9819404 | 0.74 | MGLL (0.47) | ALOX5ADRA1AADRA1BADRA1DHTR1A | |
| SCHEMBL9819189 | 0.74 | SRD5A1 (0.44) | — | |
| SCHEMBL16799216 | 0.73 | ALOX5 (0.46) | ALOX5HSD11B1ADRA1AADRA1BADRA1D | |
| SCHEMBL9819263 | 0.73 | PKM (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61236724-A | — | — | None | — | — | JP | disclosed |
| JP-60243017-A | — | — | None | — | — | JP | disclosed |
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| JP-S61236724-A | ANTISPASMODIC COMPOSITION | KYOWA HAKKO KOGYO CO LTD | 1986-10-22 | — | — | JP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| JP-S60243017-A | ANTISPASMODIC COMPOSITION | KYOWA HAKKO KOGYO CO LTD | 1985-12-03 | — | — | JP | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |