Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819404 | 0.88 | MGLL (0.47) | BCL2A1RAD51HTR1AALDH1A1 | |
| SCHEMBL11419079 | 0.87 | BCL2A1 (0.48) | BCL2A1DRD2DRD3RAD51P2RX7 | |
| SCHEMBL2470770 | 0.80 | RAD51 (0.48) | BCL2A1DRD2DRD3RAD51P2RX7 | |
| SCHEMBL9819298 | 0.78 | L3MBTL1 (0.40) | P2RX7NOTUMALDH1A1 | |
| SCHEMBL17513244 | 0.76 | DRD3 (0.51) | BCL2A1DRD2DRD3P2RX7ADRB1 | |
| SCHEMBL9819424 | 0.76 | BCL2A1 (0.49) | BCL2A1P2RX7NOTUMHTR1AALDH1A1 | |
| SCHEMBL9819361 | 0.76 | POLB (0.49) | DRD2HTR1AALDH1A1 | |
| SCHEMBL9819264 | 0.76 | ADRA1B (0.47) | BCL2A1P2RX7NOTUMHTR1AALDH1A1 | |
| SCHEMBL11425493 | 0.75 | MGLL (0.51) | BCL2A1RAD51HTR1AALDH1A1 | |
| SCHEMBL9819256 | 0.75 | MEN1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |