Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29510718 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL22493009 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6140888 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9819256 | 0.76 | MEN1 (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9819404 | 0.76 | MGLL (0.47) | ALDH1A1KMT2AMAPTL3MBTL1HTR1A | |
| SCHEMBL11183526 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9819442 | 0.75 | ADRA2C (0.44) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9819361 | 0.74 | POLB (0.49) | ALDH1A1HTTKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9819470 | 0.72 | ALDH1A1 (0.41) | ALDH1A1HTTKMT2AMAPTL3MBTL1 | |
| SCHEMBL6857955 | 0.72 | LMNA (0.51) | ALDH1A1HTTKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |