Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819116 | 0.90 | MAPK1 (0.45) | RAB9ASLC6A3NPC1CASP3SENP7 | |
| SCHEMBL9818887 | 0.89 | IDO1 (0.47) | RAPGEF3RAPGEF4IDO1RAB9ACYP1A2 | |
| SCHEMBL9819086 | 0.87 | RAPGEF3 (0.40) | RAPGEF3RAPGEF4IDO1RAB9AMEN1 | |
| SCHEMBL9819098 | 0.85 | NPC1 (0.44) | RAB9ASLC6A3NPC1CASP3SENP7 | |
| SCHEMBL9819218 | 0.85 | NPC1 (0.43) | RAB9ASLC6A3NPC1CASP3SENP7 | |
| SCHEMBL9818936 | 0.85 | RAF1 (0.45) | RAPGEF3RAPGEF4RAB9APPARGPPARD | |
| SCHEMBL9819084 | 0.83 | MAPT (0.51) | RAB9ANPC1MAPK1LMNAMEN1 | |
| SCHEMBL9818923 | 0.83 | MAPT (0.47) | RAB9ACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL9819336 | 0.83 | RAB9A (0.49) | RAB9ASLC6A3NPC1CASP3SENP7 | |
| SCHEMBL9819107 | 0.83 | GRIK1 (0.50) | RAPGEF3RAPGEF4IDO1RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |