Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819203 | 0.87 | PDK1 (0.50) | RAPGEF3RAPGEF4RXFP1KMT2AMEN1 | |
| SCHEMBL9819360 | 0.87 | RAPGEF3 (0.43) | RAPGEF3RAPGEF4KMT2AMEN1MAPT | |
| SCHEMBL9819109 | 0.85 | KMT2A (0.49) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL9818936 | 0.85 | RAF1 (0.45) | RAPGEF3RAPGEF4KMT2AMEN1MAPT | |
| SCHEMBL9819084 | 0.83 | MAPT (0.51) | KMT2AMEN1MAPTHTTRAB9A | |
| SCHEMBL9819234 | 0.83 | RAF1 (0.43) | RAPGEF3RAPGEF4MAPT | |
| SCHEMBL9819032 | 0.82 | MLYCD (0.52) | RXFP1RAB9AGSK3BVNN1MLYCD | |
| SCHEMBL9819035 | 0.82 | MLYCD (0.52) | RXFP1RAB9AGSK3BVNN1MLYCD | |
| SCHEMBL9818887 | 0.78 | IDO1 (0.47) | RAPGEF3RAPGEF4RXFP1KMT2AMEN1 | |
| SCHEMBL9818928 | 0.77 | EPHX2 (0.50) | RAPGEF3RAPGEF4RAB9AGSK3BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |