Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823051 | 0.84 | PDK2 (0.42) | PDK2EPHX2 | |
| SCHEMBL9822973 | 0.72 | HSD11B1 (0.44) | HSD11B1AGTR1AGTR2ACLYSMN1; SMN2 | |
| SCHEMBL2647877 | 0.71 | PDK2 (0.50) | PDK2HPGDSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7127239 | 0.71 | ALDH1A1 (0.48) | HSD11B1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL15401417 | 0.71 | PDK2 (0.33) | PDK2EPHX2 | |
| SCHEMBL8936373 | 0.71 | EDNRA (0.47) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL5504833 | 0.70 | PDK2 (0.46) | PDK2NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10248780 | 0.70 | ACLY (0.53) | NPC1RAB9AACLYNFKB1NFKB2 | |
| SCHEMBL8213584 | 0.69 | PDK2 (0.48) | PDK2HPGDL3MBTL1NFKB1NFKB2 | |
| SCHEMBL13846219 | 0.69 | NPSR1 (0.58) | PDK2HSD11B1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204513-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-17 | — | — | EP | disclosed |
| US-5017214-A | Herbicidal sulfonamides | LEVITT GEORGE (US) | 1991-05-21 | — | — | US | disclosed |
| US-4913726-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4786311-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4746353-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0204513-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-10 | — | — | EP | disclosed |