Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509095 | 0.83 | CYP1A2 (0.33) | BACE1BACE2APPRENHCAR3 | |
| SCHEMBL6827479 | 0.75 | BACE1 (0.43) | BACE1BACE2APPRENLMNA | |
| SCHEMBL508332 | 0.74 | ELANE (0.36) | BACE1KMT2A | |
| SCHEMBL9823653 | 0.70 | BACE1 (0.39) | BACE1BACE2APPRENLMNA | |
| SCHEMBL9482559 | 0.67 | BACE1 (0.39) | BACE1BACE2APPRENLMNA | |
| SCHEMBL509164 | 0.65 | ALDH1A1 (0.34) | — | |
| SCHEMBL9360895 | 0.64 | ALDH1A1 (0.36) | BACE1BACE2APPRENLMNA | |
| SCHEMBL7662936 | 0.60 | MMP2 (0.37) | BACE1BACE2APPRENLMNA | |
| SCHEMBL4076689 | 0.59 | BACE1 (0.40) | BACE1BACE2APPRENLMNA | |
| SCHEMBL11469864 | 0.58 | CFTR (0.39) | BACE1BACE2LMNAGLATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12285922-B2 | Method for making photofunctional contact lenses | ALCON INC. (CH) | 2025-04-29 | — | — | US | claimed |
| US-12111443-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-10-08 | — | — | US | claimed |
| EP-4313567-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | claimed |
| EP-4304842-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-4304843-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| US-11833771-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2023-12-05 | — | — | US | claimed |
| EP-3976362-B1 | METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-06-07 | — | — | EP | claimed |
| EP-4158392-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-04-05 | — | — | EP | claimed |
| US-11584097-B2 | Method for making opaque colored silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-02-21 | — | — | US | claimed |
| US-20220339895-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-10-27 | — | — | US | claimed |
| EP-0861303-A1 | WATER-BASED PIGMENTED INKS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | claimed |
| EP-0784063-A2 | Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0644904-B1 | SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME | MINNESOTA MINING & MFG (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0336762-B1 | Process for acrylamidoacylation of alcohols | MINNESOTA MINING & MFG (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1997018272-A1 | WATER-BASED PIGMENTED INKS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-22 | — | — | WO | claimed |
| US-5408002-A | Blending with thermoplastic polymers; medical diagnostic equipment | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-18 | — | — | US | claimed |
| WO-1993025594-A1 | SUPPORTS HAVING AZLACTONE-FUNCTIONAL SURFACES, ADDUCT SUPPORTS, AND METHODS OF PREPARING SAME | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-23 | — | — | WO | claimed |
| US-5262484-A | Free radical grafting to addition polymers; surface treatment with nucleophilic agents; adhesion properties for binding, immobilizing proteins; immunoassay | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-16 | — | — | US | claimed |
| US-5013795-A | Azlactone graft copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-05-07 | — | — | US | claimed |
| EP-0336762-A2 | Process for acrylamidoacylation of alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584097-B2 | Method for making opaque colored silicone hydrogel contact lenses | COIL, CRYAB, CRYAA | BACE1 4144/4885BACE2 4487/4885APP 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.