Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823653 | 0.80 | BACE1 (0.39) | BACE1LMNAGAAALDH1A1BACE2 | |
| SCHEMBL7662936 | 0.78 | MMP2 (0.37) | BACE1LMNAMMP2MMP9ALDH1A1 | |
| SCHEMBL509095 | 0.73 | CYP1A2 (0.33) | BACE1GAAMMP2MMP9ALDH1A1 | |
| SCHEMBL9823704 | 0.71 | LMNA (0.34) | BACE1LMNAMMP9 | |
| SCHEMBL7955067 | 0.69 | ELANE (0.36) | BACE1LMNAMMP2MMP9HSD11B1 | |
| SCHEMBL7955061 | 0.69 | ELANE (0.36) | BACE1LMNAMMP2MMP9HSD11B1 | |
| SCHEMBL9823594 | 0.69 | TDP1 (0.32) | CYP1A2 | |
| SCHEMBL8209492 | 0.63 | CTSD (0.37) | BACE1LMNAGAAALDH1A1HSD11B1 | |
| SCHEMBL11245064 | 0.62 | LMNA (0.38) | BACE1LMNAGAAMMP2MMP9 | |
| SCHEMBL6827479 | 0.61 | BACE1 (0.43) | BACE1LMNAMMP2MMP9BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11825845-B2 | Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-11-28 | — | — | US | claimed |
| US-11807778-B2 | Influence of partial side chain hydrolysis on the growth and morphology of reactive polymer multilayers fabricated using azlactone-functionalized polymers | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-11-07 | — | — | US | claimed |
| US-20220032338-A1 | Fabrication of Crosslinked and Reactive Nanoporous Polymer Coatings Using Spray-Based Methods | NATIONAL SCIENCE FOUNDATION | 2022-02-03 | — | — | US | claimed |
| US-20220030869-A1 | Slippery Liquid-Infused Porous Surfaces that Release Hydrophilic and Hydrophobic Agents | NATIONAL SCIENCE FOUNDATION | 2022-02-03 | — | — | US | claimed |
| US-20200181419-A1 | Influence of Partial Side Chain Hydrolysis on the Growth and Morphology of Reactive Polymer Multilayers Fabricated Using Azlactone-Functionalized Polymers | NATIONAL SCIENCE FOUNDATION | 2020-06-11 | — | — | US | claimed |
| US-10557042-B2 | Slippery liquid-infused porous surfaces that prevent microbial surface fouling | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-02-11 | — | — | US | claimed |
| US-20170022371-A1 | Slippery Anti-Fouling Surfaces Fabricated from Reactive Polymer Multilayers | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-01-26 | — | — | US | claimed |
| US-20170022372-A1 | Synthetic Surfaces with Robust and Tunable Underwater Superoleophobicity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-01-26 | — | — | US | claimed |
| US-8071210-B2 | Covalent assembly of ultrathin polymeric films | WISCOUSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-12-06 | — | — | US | claimed |
| US-20090170179-A1 | COVALENT ASSEMBLY OF ULTRATHIN POLYMERIC FILMS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-07-02 | — | — | US | claimed |
| WO-2004081538-A2 | COMPOSITIONS AND METHODS OF VINYL OXAZOLONE POLYMERIZATION | IRM, LLC | 2004-09-23 | — | — | WO | claimed |
| EP-0336762-B1 | Process for acrylamidoacylation of alcohols | MINNESOTA MINING & MFG (US) | 1997-05-28 | — | — | EP | claimed |
| EP-0413551-B1 | Stabilized polymeric dispersions | MINNESOTA MINING & MFG (US) | 1995-05-24 | — | — | EP | claimed |
| US-5239013-A | Nonlinear optically active polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| EP-0367583-B1 | FLUORINATED, ACRYLAMIDE-FUNCTIONAL MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-08-04 | — | — | EP | claimed |
| US-5075352-A | Stabilized polymeric dispersions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| EP-0413551-A2 | Stabilized polymeric dispersions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0367583-A2 | Fluorinated, acrylamide-functional monomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0336762-A2 | Process for acrylamidoacylation of alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-11 | — | — | EP | claimed |
| US-4304705-A | Radiation-curable polymers containing pendant unsaturated peptide groups derived from azlactone polymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-12-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10557042-B2 | Slippery liquid-infused porous surfaces that prevent microbial surface fouling | CLPP, MSN, Q6ZSR9 | BACE1 1641/4885LMNA 3804/4885GAA 2133/4885 |
| US-20220030869-A1 | Slippery Liquid-Infused Porous Surfaces that Release Hydrophilic and Hydrophobic Agents | CLPP, MSN, LIPA | BACE1 2192/4885LMNA 2017/4885GAA 197/4885 |
| US-11825845-B2 | Slippery liquid-infused porous surfaces that release hydrophilic and hydrophobic agents | CLPP, MSN, LIPA | BACE1 2192/4885LMNA 2017/4885GAA 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.