Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824968 | 0.75 | CXCR4 (0.43) | CXCR4ADH1BADH1CADH1AADH4 | |
| SCHEMBL8030921 | 0.75 | CXCR4 (0.48) | GNAI3GNAO1GNAI1CXCR4ADH1B | |
| SCHEMBL25344529 | 0.74 | ARG1 (0.43) | GNAI3GNAO1GNAI1PRMT3CARM1 | |
| SCHEMBL10064196 | 0.74 | ARG1 (0.43) | GNAI3GNAO1GNAI1PRMT3CARM1 | |
| SCHEMBL10064775 | 0.74 | ARG1 (0.43) | GNAI3GNAO1GNAI1PRMT3CARM1 | |
| SCHEMBL18286778 | 0.74 | ALOX15 (0.48) | GNAI3GNAO1GNAI1PRMT3CARM1 | |
| SCHEMBL9824407 | 0.74 | CHRM5 (0.50) | GNAI3GNAO1GNAI1PRMT3CARM1 | |
| SCHEMBL8043238 | 0.73 | CXCR4 (0.49) | GNAI3GNAO1GNAI1CXCR4ADH1B | |
| SCHEMBL9036781 | 0.73 | ADH1B (0.41) | CXCR4CYP2D6ADH1BADH1CADH1A | |
| SCHEMBL8047471 | 0.72 | NCF1 (0.46) | CXCR4ADH1BADH1CADH1AADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |