Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1597855 | 0.86 | NOS3 (0.42) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL4945110 | 0.85 | KDM4E (0.44) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL28683997 | 0.83 | PLAU (0.44) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL6876758 | 0.82 | LMNA (0.51) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL240654 | 0.81 | GAA (0.42) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL16057233 | 0.81 | HTT (0.41) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL29094492 | 0.80 | MAPT (0.41) | NPC1RAB9AHTTSMN1; SMN2MAPK1 | |
| SCHEMBL28682729 | 0.79 | NPC1 (0.51) | NPC1RAB9AHTTTDP1L3MBTL1 | |
| SCHEMBL7819668 | 0.79 | THRB (0.38) | NPC1RAB9AHTTATMTDP1 | |
| SCHEMBL377461 | 0.78 | LMNA (0.42) | HTTTDP1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919644-B2 | Process for producing an aromatic carbonate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| EP-2275405-A1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20070185164-A1 | Process for producing an aromatic carbonate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2007-08-09 | — | — | US | disclosed |
| US-6197918-B1 | INTERCHANGE REACTION OF DIALKYL CARBONATE AND AROMATIC ALCOHOL; CATALYSIS WITH TITANIUM HALIDE, ALKOXIDE, ARYLOXIDE, OR ACETOXIDE | GENERAL ELECTRIC COMPANY | 2001-03-06 | — | — | US | disclosed |
| EP-0192964-A2 | Phthalocyanine reactive dyes | BAYER AG (DE) | 1986-09-03 | — | — | EP | disclosed |
| EP-0075905-A2 | Water-soluble reactive phthalocyanine compounds; process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185164-A1 | Process for producing an aromatic carbonate | TYR, PAH, CYP4A11 | NPC1 3268/4885RAB9A 2722/4885HTT 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.