Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683709 | 0.87 | HTT (0.41) | HTTNPC1RAB9AATMSSTR4 | |
| SCHEMBL29094492 | 0.83 | MAPT (0.41) | GAAHTTNPC1RAB9ASSTR4 | |
| SCHEMBL982469 | 0.81 | NPC1 (0.42) | HTTNPC1RAB9AATMSSTR4 | |
| SCHEMBL4537897 | 0.81 | L3MBTL1 (0.43) | HTTNPC1RAB9ASSTR4TDP1 | |
| SCHEMBL27746423 | 0.81 | CYP1A2 (0.40) | GAANPC1RAB9ASSTR4MAPK1 | |
| SCHEMBL4538158 | 0.81 | MAPK8 (0.43) | GAAHTTNPC1SSTR4ALDH1A1 | |
| SCHEMBL27961126 | 0.79 | ALOX15 (0.40) | GAAHTTSSTR4MAPK1CYP1A2 | |
| SCHEMBL1597855 | 0.79 | NOS3 (0.42) | HTTNPC1RAB9AATMSSTR4 | |
| SCHEMBL21034695 | 0.78 | ALOX15 (0.46) | GAASSTR4SMN1; SMN2SSTR1KMT2A | |
| SCHEMBL4945110 | 0.78 | KDM4E (0.44) | HTTNPC1RAB9AATMSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859803-B2 | Process for production of ketomalonic acid compounds or hydrates thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2447243-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | ME1, CA6, ME3 | GAA 240/4885HTT 1619/4885NPC1 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.