Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824121 | 0.90 | GNAI3 (0.40) | KMT2AMEN1L3MBTL1CARM1PRMT6 | |
| SCHEMBL9823964 | 0.88 | MEN1 (0.39) | KMT2AMEN1L3MBTL1BCHE | |
| SCHEMBL9825152 | 0.81 | BCHE (0.35) | KMT2AMEN1BCHECARM1PRMT6 | |
| SCHEMBL13006566 | 0.81 | MEN1 (0.40) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL9824832 | 0.80 | GNAO1 (0.45) | CARM1PRMT6ALOX15 | |
| SCHEMBL9823863 | 0.79 | GNAI3 (0.42) | KMT2AMEN1BCHECARM1PRMT6 | |
| SCHEMBL9824712 | 0.76 | MEN1 (0.40) | KMT2AMEN1L3MBTL1BCHE | |
| SCHEMBL11615967 | 0.75 | ALOX15 (0.41) | BCHECARM1PRMT6ALOX15 | |
| SCHEMBL3897612 | 0.74 | CYP2D6 (0.45) | BCHECARM1PRMT6ALOX15 | |
| SCHEMBL10064309 | 0.74 | CYP2D6 (0.45) | BCHECARM1PRMT6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |