SCHEMBL9824947

SCHEMBL9824947

Cc1cccc2c3cscc3cc-2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
RAB9A P51151 3/20 0.36
ENPP1 P22413 1/20 0.35
SLC9A1 P19634 1/20 0.35
ATP4A P20648 2/20 0.34
ATP4B P51164 2/20 0.34
NPC1 O15118 2/20 0.33
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
ADORA1 P30542 2/20 0.33
MAOB P27338 1/20 0.33
ENPP3 O14638 1/20 0.33
ADORA2A P29274 1/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876284 0.94 ADORA1 (0.42) RAB9AENPP1SLC9A1NPC1ALDH1A1
SCHEMBL9826546 0.78 RXRA (0.36) ALDH1A1KDM4ETP53HPGDSMN1; SMN2
SCHEMBL9824831 0.78 PTGS2 (0.40) ACHERAB9ANPC1MEN1ALDH1A1
SCHEMBL9825010 0.77 CYP2A6 (0.41) RAB9AMEN1ALDH1A1KMT2AHSD17B10
SCHEMBL24063287 0.71 CYP2A6 (0.48) ACHERAB9ANPC1MEN1ALDH1A1
M-Xylene SCHEMBL3470864 0.70 ACHE (0.57) ACHENPC1ALDH1A1KDM4ETP53
SCHEMBL4323024 0.68 ENPP1 (0.48) RAB9AENPP1NPC1ALDH1A1KMT2A
SCHEMBL9825320 0.68 SLC9A1 (0.38) ACHEENPP1SLC9A1MEN1ALDH1A1
SCHEMBL838870 0.66 ENPP3 (0.47) RAB9AENPP1NPC1ALDH1A1MAOB
SCHEMBL30545233 0.66 ENPP3 (0.47) RAB9AENPP1NPC1ALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0187015-B1 SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI KASEI CORPORATION (JP) 1991-05-29 EP disclosed